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Interestingly, HSP90 inhibitors promote BRD4 degradation but do not affect its polyubiquitylation efficiency, indicating that HSP90 inhibitors promote targeted degradation after the ubiquitylation step

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Q., Ajmo, J

Targeting GSH synthesis/utilization therefore represents a potential means of rendering tumor cells more susceptible to different treatment options such as chemotherapy and radiotherapy

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[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Tanaka M., Tuka B., Vcsei L
