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Intricacies of TGF- signaling in Treg and Th17 cell biology

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[DOI] [PubMed] [Google Scholar] 62.Klatt P., Molina E.P., Lacoba M.G., Padilla C.A., MartnezGalisteo E., Barcena J., Lamas S

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KRAS is a crucial downstream effector of the epidermal growth factor receptor (EGFR), and mutations at these codons result in the constitutive activation of the Ras/Raf/MEK/ERK and PI3K/Akt pathways, making EGFR signaling uncontrollable [6]