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doi: 10.1158/2159-8290.CD-19-1228 89 DoepnerMLeeIYRidkyTW

Adipocyte prolactin: regulation of release and putative functions

It follows with increased melanin production that leads to hyperpigmentation and reduced effect of glutathione

The progressive ROS damage leads to release of mitochondrial components, some of which, such as cytochrome c , can trigger the intrinsic apoptotic program
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10.1016/j.jhep.2018.12.003 50 LaiY