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Despite the small size of the tri- and tetrapeptides, a property ultimately necessary for BBB permeability, these molecules were metabolically unstable and likely too hydrophilic to breach the BBB

Gustavo Lazo, Andrea Schilling, Pablo Bonvehi, Maisa Kairalla To view or add a comment, sign in Just published - a re-analysis of the FDA's risk-benefit analysis of the Moderna COVID vaccine, focusing on young males 18-25 years old

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Chronic users may experience persistent cognitive impairments, including memory problems and difficulty concentrating

PEASE, JOHN A

The CMAJ guidance A guidance article published in the Canadian Medical Association Journal (CMAJ) on glucagon-like peptide-1 receptor agonists during pregnancy and lactation concluded that while the safety data is limited, the pharmacological properties of GLP-1 agonists (large molecular weight, poor oral bioavailability) suggest low theoretical risk during breastfeeding