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10.1681/asn.2010050510 Pubmed Abstract CrossRef Google Scholar View reference in article 13

-Arrs were shown to interact more transiently with 1 -AR than 2 -AR in response to agonist-stimulated cells, possibly due to weakened phosphorylation of 1 -AR, which in turn will make the interaction of -Arrs with the 1 -AR too weak to recruit ubiquitinating enzymes (Liang and Fishman, 2004)

In particular, 10( E )-9-oxo-12(13)-EpOME promoted the production of aldosterone, a hormone regulating blood pressure, at low doses (from 0.5 to 5 mol/L in vitro ), and inhibited its production at higher doses, 185 while both 11( E )-10-oxo-OME and 9( Z ),15( Z )-13-oxo-ODE stimulated production of a cholecystokinin, a gut hormone that helps digestion and reduces appetite, via activation of GPR40 (further demonstrating the role of octadecanoids in attenuating diet)