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25 Whether enhanced total body lipogenesis that occurs in humans in response to chronic GC exposure reflects adipose tissue or hepatic lipogenesis is not known but, based on the higher contribution of hepatic lipogenesis to whole-body lipogenesis, 26 one would expect GC-induced lipogenesis to be primarily hepatic in origin
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Such research opens possibilities for developing GPX4-based OA treatments (Xiao et al., 2024)
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