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It creates a heart-like shape with a crisp upper contour and a smoother transition between the top and bottom lips

Used in over 40 countries with thousands of satisfied patients worldwide
[DOI] [PubMed] [Google Scholar] 54.Allen J, Bradley RD

The m was measured using Rhodamine 123

doi: 10.1053/j.gastro.2019.01.002 25 AgrawalMChristensenHSBgstedMColombelJFJessTAllinKH

Interestingly, these mutants do not show a decrease in their basal energy expenditure, implying a metabolic reprograming toward the consumption of non-lipid sources, such as carbohydrates and/or amino acids
