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Under physiological hypoxia, low oxygen levels in blood lead to succinate accumulation [56]

Abbreviations 6-OHDA 6-Hydroxydopamine AD Alzheimer's disease BACE1 -Site amyloid precursor protein cleaving enzyme 1 BDNF Brain-derived neurotrophic factor CNS Central nervous system CSF Cerebrospinal fluid EMA European medicines agency FGF-1 Fibroblast growth factor 1 MAD Mucosal atomization device PD Parkinson's disease siRNA Small interfering RNA Author contributions ID wrote the original draft and prepared the figures

95-B , 305313 (2013)

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Alcohol Use by Youth