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[DOI] [PMC free article] [PubMed] [Google Scholar] Bech A

These studies demonstrated that a large amount of copper intake can result in oxidative damage by activating the antioxidant protection signals mitogen-activated protein kinase 14 (MAPK14)/the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1)/NAD(P)H:quinone oxidoreductase 1 (NQO1) pathway, inhibiting cAMP-response element binding protein (CREB)/Brain-derived neurotrophic factor (BDNF) pathway or PI3K/AKT/mTOR pathway to induce apoptosis or autophagy (Figure 2

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Taking vitamin B 12 supplements affects the genes expressed by bacteria living on our skin, report researchers at the University of California, Los Angeles (UCLA) in Science Translational Medicine [1] on 24 June 2015

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