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A Kir2.3-like K+ conductance in mouse cortical collecting duct principal cells

Nicotinamide adenine dinucleotide (NADH) and acetyl-CoA, two metabolic intermediates produced in the course of FAO, induce activation of PDK, which in turn phospho-inactivates the E1 subunit of the PDH complex, leading to lower rates of glucose oxidation and higher rates of lactate release 70

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Fatty acids can also undergo -oxidation by action of a microsomal oxidase that uses molecular oxygen, and both an alcohol and aldehyde dehydrogenase to produce dicarboxylic acids, molecules with a carboxyl group at each end [75, 76]

[DOI] [PubMed] [Google Scholar] 498.Tezze C, Romanello V, Sandri M