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Description
About half of the bodys cholesterol is interspersed in the lipid bilayer of cell membranes (Figure 17.6 Schematic Diagram of a Cell Membrane)
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Subsequent lecithin-cholesterol acyltransferase (LCAT)-mediated cholesterol esterification and addition of core lipids convert this to mature spherical HDL composed of cholesterol, triglycerides and apolipoproteins
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Oral supplements must first pass through the digestive tract, where a portion of the active compound can be degraded or poorly absorbed, especially if gastrointestinal issues are present
