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This approach enabled the analysis of minimal sample quantities while yielding uniformly distributed spots on the MALDI target, successfully detecting picomolar amounts of disaccharides, octasulfated sucrose, and the sodium salt of octasulfated pentasaccharide (Arixtra)

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To establish a connection with the NO-system, l-NAME (5 mg/kg intraperitoneally) (worsening) and/or L-arginine (100 mg/kg intraperitoneally) (beneficial effect) were given alone or together