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Nerve areas and root, with higher blood vessel density, showed higher intensity level of CD31 signal, as depicted in Fig
Pyruvate can, in turn, be transformed to Lactate, restoring NAD + needed for anaerobic glycolysis and production of ATP (Figure 1B)
In an experimental model of ischemic optic neuropathy, treatment with bardoxolone methyl exerts a myelin-preserving impact on RGC survival, achieved by enhancing the transcription of ferroptosis-associated protective factors, namely HO-1 and NQO1 (141)
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