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Description
Yes, several modifiers may apply depending on the clinical scenario

How much bacteriostatic water should I add to AOD-9604
What is missing There is no published human pharmacokinetic study of subcutaneous AOD-9604, no published human topical or intranasal exposure data, no Phase 3 efficacy trial, no long-term safety data beyond 24 weeks, and no published human cartilage or joint outcome data

Some do a short loading phase, then move to maintenance

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