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10.3389/fcvm.2022.1090616 155 XiongP.NiuL.TalaeiS.Kord-VarkanehH.ClarkC

PLoS ONE 14(12):e0227271

The activation of metabolic pathways related to mitochondria and the production of energy through the NAD + and SIRT1 is currently suggested as a therapeutic strategy (Yang and Sauve, 2016

Moreover, CRP activates complement cascades and induces expression of proinflammatory cytokines, such as interleukin-6 and TNF- (Friend et al., 2022

These findings indicated that mitochondrial oxidative stress was increased in the Fabry kidney organoids

Results The enzyme samples are incubated in a phosphate buffer containing specific concentrations of glutathione (GSH) and peroxide and then incubated for a suitable time to react before Ellman's reagent (5,5-dithiobis-(2-nitrobenzoic acid) (DTNB) is added