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Description
SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo

However, PSPH ser/gly pathway enzyme genetic aberrations are not acknowledged as important drivers of GBM because of the close proximity of EGFR (chr7:5501901755211628) to PSPH (chr7:5601105156051604), which is a common driver oncogene in GBM [47,48,49]

Z., & Overgaard, V

Reinforcing this finding, the depletion of lipid droplets driven by the inhibition of diacylglycerol-acyltransferase 1 (DGAT1) completely prevented lipid peroxidation induced by DHAA or by IKE + DHAA (Fig

It seems that tilting the balance in either direction toward free radical excess or deficiency may be detrimental

Cytoplasmatic ROS levels Cells were seeded and allowed to attach overnight
