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The microbiome matters: its impact on cancer development and therapeutic responses

Other common side effects of dupilumab include cold sores, injection site reactions, joint pain and an increase in the number of eosinophils (a type of white blood cell) in the blood

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However, the clinical application of PDK inhibition must be approached cautiously, as systemic toxicity may arise from off-target effects in vital organs that rely on PDK-mediated metabolic regulation for physiological homeostasis