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Glutathione S-transferase A1 - a sensitive marker of alcoholic injury on primary hepatocytes

Amyloid beta In his 1907 article describing the disease, Alzheimers post-mortem analysis of Auguste Deter, revealed intracellular neurofibrillary tangles and minute miliary foci deposited extracellularly as amyloid plaques (Glenner and Wong, 1984)

In this scenario of cellular diversity emerges the concept of selective neuronal vulnerability (SNV)

Chaput JP, Dutil C, Featherstone R et al (2020) Sleep duration and health in adults: an overview of systematic reviews

doi: 10.1186/1476-511x-11-3, 28

16 Despite increases in NAC concentrations, there was no observed increase in CSF total or reduced GSH concentrations, presumably because the conversion of NAC to GSH occurs intracellularly