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These agents consistently induce the expression of CHAC1 across different cancer types, often leading to apoptosis, increased oxidative stress, and enhanced ferroptosis

We developed an optimized prototype for respiratory tract delivery customized for NonHuman Primate (NHP) in spontaneous breathing by adapting a vibrating mesh nebulizer (VMN) from Aerogen (Aeroneb solo) to a facemask fitted with unidirectional valves

As it is not a topical cream there is no concern regarding allergic reaction, texture, or contra-indications after any treatments or therapies

This is what we find, as the R370A and R413A mutants are completely or significantly inactive, respectively (Fig

doi: 10.1016/j.arcmed.2012.03.008