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A safety review in the Journal of Obesity & Food Metabolism describes six randomized, double-blind, placebo-controlled trials evaluating AOD-9604, including oral dosing studies and longer phase II programs

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Rare Earth 29 , 155159 (2011)

Formulation & Handling For optimal stability and integrity, lyophilized GHK-Cu (Copper Peptide) should be stored in a freezer at or below -20C, protected from direct light

A recent study also shows that blocking IGF1R-mediated signaling reduces cell proliferation and increases cells sensitivity to the destructive effects of ionizing radiation mediated by down-regulation of BRCA2, a mediator of HR, suggesting that IGF1R is a target for enhancing tumor sensitivity to radiotherapy (Venkatachalam et al., 2017)

IGFR expression has been shown in porcine Leydig and Sertoli cells (83)