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On top of that, there are some side effects to keep in mind, too
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However, the mutant strains expressing non-phosphorylatable- vadK:vadK His422Ala , phosphomimetic vadK:vadK His422Asp or a non-functional ATP-binding site vadK:vadK Arg106Lys were unable to grow (Appendix Fig

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Other reported effects include: Headaches and dizziness Nausea and gastrointestinal discomfort Allergic reactions to B12 formulations (rare) If you experience symptoms suggesting a severe allergic reaction (difficulty breathing, severe rash, swelling of face/throat), seek emergency medical attention immediately by calling 999 or attending A&E