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However, in the presence of oxidative or nitrosative stress, GST can form homodimers that alter the reduced states of cysteine residues in its structure, resulting in JNK dissociation from the GSTJNK heterocomplex and causing subsequent activation of the c-Jun protein

The use of green tea extract and curcumin is worth mentioning

[PubMed 822144] 420
Zhao, Y., Xiao, J., Gong, S., Clara, J

Choice B: Black flies ( Simulium species) are the primary vectors for Onchocerca volvulus , a tissue nematode endemic to sub-Saharan Africa and parts of Latin America

Usually yes
