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Tian J-L, Si X, Shu C, et al

Altered Redox Regulation and S-Glutathionylation of BiP Contribute to Bortezomib Resistance in Multiple Myeloma

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Notably, an enzyme detoxifying PAP into AMP known as FRY1/SAL1 is localized in chloroplasts (Estavillo et al., 2011), and therefore the transport of PAP into chloroplasts is both logical and essential for the cell