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488 In the clinic, cognitive tests and patient/carer history remain the mainstay methods for identifying AD signs and symptoms (amnesia, disorientation, mood changes, etc.), and additional laboratory tests (full blood count, metabolic panel, etc.) are used to rule out differential diagnoses (e.g., metabolic causes of dementia), often with radiological imaging (MRI/PET) to assess neurodegeneration and rule out vascular dementia

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