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Also, the 3D crystallographic structure of tyrosinase from Agaricus bisporus mushroom with a tropolone inhibitor (PDB ID: 2Y9X) 37 was downloaded from the RCSB protein database ( 38

However, this method of FXN rescue would not be beneficial for non-mitotic cells such as CNS neurons

Cancer Research Communications 5(9):1566-1573, 2025

Caspase-3-dependent cleavage of the glutamate-L-cysteine ligase catalytic subunit during apoptotic cell death

19 After being absorbed into intestinal epithelial cells, some iron is stored as ferritin, while the rest enters the blood circulation through membrane ferroportin (FPN)