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miR-101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells
Symptoms typically present in adulthood with motor impairments, psychiatric symptoms, and progressive cognitive decline

And the treatment of CNS tumors such as glioma differs from other tumors, the use of ferroptosis inducers requires consideration of BBB penetration for optimal drug concentrations

Immunohorizons 6 , 476487 (2022)

[DOI] [PMC free article] [PubMed] [Google Scholar] de Puig H
