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Description
Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics

Invest Ophthalmol Vis Sci 55:69216933
& Loku Pulukkuttige, J

Moreover, this oxygen dependency poses a serious risk of oxidative stress and creates an oxygen paradox or aerobic-life paradox (Hoseinifar et al., 2020b)

This effect was evidenced by alterations in total and ferrous iron levels in the hippocampus and an increase in the expression of PEBP1, ERK1/2, and key ferroptosis-related proteins, including GPX4, FTH1, ACSL4, and COX2 (Jiao et al., 2021)
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