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Bandeen-Roche, D.E

For B12 deficiency, a typical injection dose is 1,000 mcg once a week for 4 to 8 weeks and then 1,000 mcg once a month

On the other hand, those with methylation issues (MTHFR gene mutations carriers, for instance) do best on methylated B12, that is, methylcobalamin

If high doses of vitamin B12 supplements are suspected to be causing side effects, the first step is to stop taking vitamin B12 supplements

This can ultimately cause a type of anemia

If you have a B-12 deficiency, it can be more challenging to lose weight, and you might feel sluggish or tired, so B-12 injections can help boost your energy and metabolism.