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Furthermore, insulin resistance (IR) and chronic hyperglycemia (CH) associated with diabetes exacerbate mitochondrial damage by increasing the production of reactive oxygen species (ROS) within mitochondria

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Beyond biochemical outcomes, improvements were also noted in sleep-related parameters, including sleep architecture, efficiency, respiratory function, and snoring

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Obstructive sleep apnea (OSA) and pulmonary arterial hypertension (PAH) David Flenley coined the term Overlap Syndrome (OS) when he described Obstructive Sleep Apnea (OSA) in patients with COPD and showed that they had a higher risk of mortality and ECOPD 119

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