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BSO treatment decreased intracellular GSH levels from 40 to 0.8 nmol/10 6 cells, and further decreased below detection limits following QI exposure (data not shown)

Reactive oxygen species (ROS) are normally produced in the cell during mitochondrial electron transfer chain (ETC) or redox reactions and are in fact a necessary component of cellular homeostasis

10.1016/0378-4274(95)03532-x 143 Wong-EkkabutJ.XuZ.TriampoW.TangI

Diagnosis of MSA is missed even at tertiary reference centers, in 50%75% of cases (Litvan et al., 1997)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Maire T, Youk H