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In addition to its tumor-intrinsic functions, JMJD3 also modulates the tumor immune microenvironment

10.1016/j.reprotox.2023.108356 39 LyonsD

In a study by Rosato and coworkers who evaluated the NAC effects on vascular system function in Systemic Sclerosis patients, authors concluded that NAC improved vascular renal function in patients with low severity of disease (NAC dosage: 15 mg/kg/hour for 5 hours)[62]

The delivery systems established are visualised in Figure 3, while Table 1, at the end of this section, summarises the nanotechnological strategies described throughout the text

Abundant evidence indicates sex differences in the P-gp transport (Baris et al., 2006