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These data have important clinical implications and inform the public regarding the risk of combining the recreational use of cannabis with psychostimulants to enhance cognitive performance or in the treatment of ADHD

One well studied case is that of busulfan (as shown in Scheme 8) [126], an anti-cancer drug now widely employed to suppress lymphocytes and blood cell stem precursors prior to performing life-saving bone marrow transplantation in malignant diseases and in inborn blood diseases [127,128]

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Methionine synthase is particularly important as it is involved in the folate cycle, which is essential for DNA synthesis

For example, basic fibroblast growth factor (bFGF) and epidermal growth factor (EGF) promote fibroblast activation, collagen synthesis, and vascularization [3], while antimicrobial peptides (AMPs) contribute to infection control and immune modulation at wound sites [21, 22]

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