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HEPATOCYTE CELL DEATH MECHANISMS AFTER APAP TOXICITY The mode of cell death after APAP-induced liver injury was controversial initially, since a number of mechanistic steps in the process, such as mitochondrial Bax translocation, release of cytochrome c64,79,88, and nuclear DNA fragmentation32, were similar to that seen during apoptosis (Fig

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MSC-based cell therapy MSC-based cell therapy in preclinical studies Several animal studies have demonstrated that MSC therapy is a promising novel intervention for ARDS

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