Glutathione Reductase human
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Description
Saudi Pharmacol J
Samples were briefly centrifuged at 2000g for 2 minutes to pellet hemibrain, then supernatant was carefully removed
It binds to KRAS G12C mutants and locks KRAS in an inactive state, thereby irreversibly inhibiting KRAS activity
Bo qun ng cch: Glutathione nhy cm vi nhit v nh sng
Furthermore, the induction of FSP1 condensate formation within tumor cells triggers the phase separation of FSP1, ultimately inducing ferroptosis in cancer cells
In contrast, HIF2 KO cells presented an accumulation of GSSG, indicating reduced capacity to overcome radiation-induced oxidative stress (Figure S7B)
