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Genotoxicidad / mutagenicidad : estudios in vitro (test de Ames) negativos

Although the mechanistic explanation for this observation is still under investigation, recent evidence points to the possibility of non-genetic sperm mediated effects on preimplantation embryo development (Tomar et al., 2024)

10.1074/jbc.M500356200 18 De DomenicoI.WardD

Physical compatibility of vasopressin with medications commonly used in cardiac arrest

Mutations in the MBD of MECP2, affecting its DNA-binding affinity, can be classified into three categories: those causing significant reduction (e.g., L110V, S134C, P152R, D156E), moderate increase (e.g., A140V, R111G), and minimal or slight effects (e.g., F155S, R106Q, R106W, R133C, R133H) on MECP2s DNA-binding affinity (34, 106, 107)

According to Li et al., women with PCOS had significantly higher levels of lncRNA H19 expression in peripheral blood leukocytes than did healthy controls