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60 kcal% fat, 20 kcal% carbohydrate, 20 kcal% protein, Research Diets, Inc

When levels drop below optimal ranges, the body signals distress through fatigue, weakness, and neurological complications

None of these pathways directly substitute for another, which is part of why researchers interested in a fuller picture of metabolic regulation may look at all three within the same body of literature not to combine effects, but to understand how separate systems might interact at a mechanistic level