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doi: 10.1089/ars.2011.4391 9 LinWWangCLiuGBiCWangXZhouQet al

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5-amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide using S-adenosylmethionine (SAM)

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Often, this results in a smaller appetite

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This competition disrupted senescence and excluded active nuclear p53 to the cytosol

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