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However, elderly patients on long-term PPI therapy should be monitored for hypomagnesemia, vitamin B12 deficiency, and bone fracture risk, as these risks increase with age and prolonged use
The World Health Organization reports that nearly one-third of women of reproductive age and 37% of pregnant women worldwide suffer from anemia

In some situations, doctors may also order additional tests, such as methylmalonic acid (MMA), to detect early B12 deficiency

If experiencing anaphylaxis, or a severe allergic reaction, it is also best to seek medical advice
