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Astrocytes maintain their antioxidative functions through two primary mechanisms: the Nrf2keap1antioxidant response element (ARE) pathway and glutathione (GSH) synthesis

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Diclofenac (50 g/mL) served as a positive control

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It demonstrates potent cytoprotective effects[2] across diverse tissues, promoting cell survival and regeneration while exhibiting an excellent preclinical safety profile

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