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After three days, the spleen of the immunized mice was harvested, lysed off red blood cells, and the splenocytes were fused with SP2/0 cell lines

However, when the precursor to sulforaphane, glucoraphanin, was provided in the mothers food during pregnancy and lactation, the pups had significant improvement in cognitive deficits and social interaction and protection from poly(I:C) induced parvalbumin-positive cell loss

The lack of success at Phase III was attributed to factors such as high baseline immunosuppressive therapy in patients and complex disease mechanisms in SLE, potentially limiting the application of Rituximab as a monotherapy in SLE (119)

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Dean OM, van den Buuse M, Bush AI, Copolov DL, Ng F, Dodd S, Berk M

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