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The enzyme glutathione reductase (GR) , utilizing the coenzyme NADPH, steps in to break the disulfide bond, recycling GSSG back into the active, reduced GSH state

The TBI-induced cerebral ischemia causes excessive glutamate release, which elevates intracellular Ca 2+ levels leading to excitotoxicity and precipitation of seizures

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Patients were randomized to receive pemetrexed 500 mg/m2 intravenously every 21 days or placebo until disease progression or intolerable toxicity

Glutathione, a vital cellular antioxidant, plays a crucial role in maintaining cellular health

This packaging allows the glutathione to pass through the stomach and into the small intestine, where it's absorbed into the bloodstream and delivered to cells