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IsoNet, an isotopologue similarity networking strategy based on mass spectrometry-resolved stable-isotope tracing metabolomics, enables ab initio elucidation of unknown metabolites and their reactions, which is applied to the glutathione metabolic reaction network.

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Researchers use DSIP in rodent EEG studies, neuroendocrine-stress models, and comparative neuropeptide pharmacology

Studie: Diese Studie zeigte, dass die Supplementierung mit Niacin (50 mg/kg/Tag) bei Ratten die durch Methylquecksilber induzierte berproduktion von reaktiven Sauerstoffspezies (ROS) und die Oxidation von Glutathion (GSH) in Lebermitochondrien reduzierte, was auf eine schtzende Wirkung von Niacin gegen oxidativen Stress hinweist