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Kidney disease: Optimisation of renal function, management of chronic kidney disease according to NICE guidelines (NG203), and nephrology referral if appropriate

The incidence of adverse experiences described in the Table below are based on data from a short-term clinical trial in vitamin B12 deficient patients in hematologic remission receiving Nascobal (Cyanocobalamin, USP) Gel for Intranasal Administration (N=24) and intramuscular vitamin B12 (N=25)

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Krishnan A, Nooka AK, Chari A, et al

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An earlier 12-week Phase 2b trial with 300 obese patients produced more encouraging numbers: the 1 mg dose group lost an average of 2.8 kg compared to 0.8 kg for placebo, with small but consistent improvements in cholesterol profiles and a reduction in patients with impaired glucose tolerance