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In GBM mouse models, overexpression of Romo1 induces ROS generation via mTORC1 signalling, which in turn promotes the polarization of bone marrow-derived macrophages (BMDMs) to the M2 type, resulting in a significant suppressive TME (133)

Patients often present with an insidious onset of dry cough and dyspnea

The Adjusted R 2 value being close to the R 2 value suggests that adding additional variables does not significantly affect the model's performance

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Wang YT, Linden DJ
Wang, W.-Z