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This regulatory history is worth understanding for context: the compound has more human safety and pharmacokinetic data behind it than many newer research peptides, but the pivotal efficacy trial ultimately did not succeed, which is why AOD9604 never reached the market as an approved obesity drug

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16 B12 has a half-life of approximately six days in the blood, which usually means that it takes around six days before half of the injected amount is eliminated from the body

Some of these events have been reported in patients without known underlying renal disease

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