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Safety Profile Recognized by the Cosmetic Ingredient Review (CIR) as safe INCI: Copper Tripeptide-1 CAS: 49557-75-7 Molecular Formula: C14H24N6O4 Used correctly, GHK-Cu is gentle enough for long-term daily application , even for sensitive and menopausal skin

[DOI] [PubMed] [Google Scholar] Wong 2006 Wong SSL, Wilczynski NL, Haynes RB

We further examined the protein expression and activation states of Smad2 and Smad3, which are downstream effectors of TGF signaling, in NP cells treated with L929 conditioned media

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