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The secondary outcome measurements were improvement of neurologic symptoms and hematologic findings (serum folate, homocysteine, ferritin, iron, total iron binding capacity, transferrin, and mean corpuscular volume)

This design mirrors the lipolytic region of GH while avoiding broader growth-promoting effects

Cecal samples Cecal weight was measured since the weight of this portion of the intestine appears to be highly influenced by the microbiome (e.g., certain antibiotic treatments dramatically increase cecal weight 27,28,29,30,31 but not the colon 27 )

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