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Previous researches demonstrated that the reduction of melatonin levels in CSF and serum leads to the aggravation of AD neuropathology [37, 38, 63]

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C9SN, a carrier-free immunotherapeutic nano-enhancer with dual synergistic effects, was constructed using self-assembly of the GLS inhibitor compound 968 (C968) and the photosensitizer Chlorin e6

the BBB thus also limits the delivery of xenobiotics (such as drugs and diagnostic agents) to the brain, which complicates classical drug therapy (i.e

J Neurochem 105:287295 Tripatara P, Patel NS, Brancaleone V, Renshaw D, Rocha J, Sepodes B et al (2009) Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury: an in vivo study

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