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Of the 220 articles obtained, 11 were finally included in this systematic review

Accordingly, its long-term neurotrophic and analgesic activity has been confirmed in animal models of chronic inflammatory and neuropathic pain and in clinical studies in patients with peripheral neuropathies

According to studies, plant-based diets, such as the Mediterranean diet, reduce TMAO levels by encouraging a microbiota composition that suppresses TMA-producing bacteria

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Figure 1 Lipopolysaccharides (LPS) play a critical role in intestinal mucosal dysfunction