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This phenotype was accompanied by accumulation of intracellular ferrous iron and lipid peroxides and the extracellular release of malondialdehyde, all indicative of redox stress, and increased levels of lactate dehydrogenase in the culture supernatant, indicating enhanced cell injury

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Clinical treatment with dopamine agonists (DA) is effective in 80 to 90% of patients with prolactinoma leading to normal serum prolactin levels and tumor reduction